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KMID : 0378019890320010129
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New Medical Journal
1989 Volume.32 No. 1 p.129 ~ p.135
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Clinical Study on Antihypertensive Effect of Doxazosin
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Abstract
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To evaluate the antihypertensive effect of doxazosin, 67 patients with essential hypertension were studied. .
Among them, 44 patients were evaluable for the study and the results areas follows;
1) The reduction of blood pressure from baseline after 12 weeks therapy of doxazosin was 26.9 mmHg
systolic and 15.8 mmHg diastolic blood pressure. ;
2) The efficacy of doxazosin therapy was successful in 90.9% and failed in 9.0%. In 35 patients with
mild to moderate hypertension, 97% of patients blood pressure was normalized.
3) The most frequent dose of doxazosin used was 4mg/day and there were no significant side effects
clinically and laboratory test.
This results suggested that doxazosin could be used as monotherapy in patients with mild to moderate hypertension.
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